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    CBC (Cannabichromene)

    CBC Isolate (>95% pure).

    Naturally-occurring CBC Molecule for More Effective Plant Medicine and Remedies

    CBC is not scheduled as a controlled substance. At room temperatures, CBC does not crystallize but remains as a liquid.

    PPM’s proprietary pocessing to obtain CBC mimics the natural pathway in the plant where CBC is derived from CBGA, the “mother of all cannabinoids”, and is converted during the plant’s maturation into CBC based on conditions, such as oxidative processes like sunlight and heat, as well as enzymatic processes.

    Cannabichromene Molecule

    Formula: C21H30O2

    Molar mass: 314.46 g/mol

    ChemSpider ID: 28064

    PPM’s CBC concentrate is ideally suited for fully customizable bespoke formulations and contains other phytocompounds that work synergistically with CBC in the entourage effect.

    The purity of PPM’s CBC concentrate has been tested by HPLC, LC-MS, GCMS, NMR, IR, melting point, and elemental analysis. All analytical test results demonstrate the high quality and purity of PPM’s CBC isolate.

    Potential Anti-Microbial, Anti-Fungal and Anti-Inflammatory Effects of CBC

    CBC (Cannabichromene) PPM

    Naturally derived CBC is one of the rare cannabinoids that is very versatile with many potential health benefits. During the cannabis plant’s life, and depending on genetics and environmental growing conditions, CBG converts and produces CBC in two different forms by means of an activated enzyme process. These two different CBC molecules are called chiral isomers or enantiomers and and have different three-dimensional structures on the carbon atom that is called the stereocenter (red arrow). This means that the two isomers could interact differently with the endocannabinoid receptors. But as of today, in clinical animal trials, it is the mixture of these two naturally derived cannabinoids that is studied for their biological activity and physiological properties. More studies are needed to determine if it is both isomers that are bioactive or just one of the two, or if they work together synergistically though the entourage effect.

    It was shown that CBC exhibits potent activity against several Staphylococcus Aureus (MRSA) strains (Hyperlink 1) and has antifungal properties (Hyperlink 2). It has also been reported that CBC is superior in efficacy to phenylbutazone which is a nonsteroidal anti-inflammatory drug (NSAID) that has been discontinued for human use due to its strong side effects. (Hyperlink 3)

    CBC also interacts with proteins in the body that are responsible for pain control (Hyperlink 4) and is not binding to the CB1 receptor in the endocannabinoid system, which makes CBC non-euphoria inducing.  However, this rare cannabinoid binds to the CB2 receptor which modulates inflammation, (Hyperlink 5) and also has the potential to be used in treating potential skin conditions, such as acne, because CBC has been shown to significantly decrease acne inducing lipids. (Hyperlink 6)

    CBC’s qualities have captured the attention of both researchers, health and wellness companies, the pharmaceutical industry and consumers because of the various studies showing the naturally occurring’s molecules potential to treat various health conditions.  Some researchers posit CBC may also be useful in addressing various mental health issues and may prevent the absorption of endocannabinoid anandamide that has shown to have anti-tumor efficacy. (Hyperlink 7 and 8)

    All studies reported here have been published in the scientific peer-reviewed literature. From our survey and in our judgement, the articles cited are recent and relevant to the potential health and wellness benefits of rare cannabinoids but does not include all literature that exists. It must be noted that most clinical trials have been performed on the animal model or in vitro on cells. More research is required including human trials to demonstrate and understand efficacy, serving and dosing sizes, potential side effects, effects on at-risk populations, and drug interactions related to the use of minor cannabinoids. 

    Technical Data Sheet

    PPM wholesales bulk ingredients intended for dilution and formulation prior to sale to end-use customers.

    These statements have not been evaluated by the Food and Drug Administration.  Any product mentioned is not intended to diagnose, treat, cure, or prevent any disease. 

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