Chocolate and CBN – a most natural pairing!
Chocolate and Cannabinoids: They go great together. A near-perfect delivery mode - enhanced bioavailability, great taste, antioxidant-rich, the list goes on. Analytical testing of CBN, CBG, THC, and CBD in a chocolate matrix brings in canna chemistry from both the processing as well as analytical chemistry domains. Proper dosing/serving
Cannabinoid Gummies to the Rescue! CBN, CBC, CBG, THCV
Personalized Remedies and Medicines with Gummies For nearly 100 years, gummies - those stick to the teeth, fruity, sweet, fun to pop in the mouth - bears, worms, fish, rings, fried eggs, soda bottles, dinosaurs - were candy. In the last ten or so years, they have been the
Do Not Judge Cannabinoid Isolates Based Solely on Color – CBDV, THCV, D*T and Others
Did you know that a cannabinoid can be like a chameleon in the sense of being different colors based on different conditional factors? In canna chemistry, finished isolate products, even clear liquids and white powders, are not necessarily a determinant of purity. It is the same situation in the
Combating Chronic Pain Without Opiods – Cannabinoids like CBDV, CBC, CBN and CBD are Coming to the Rescue via their Activity on TRP Channels
Bully, Torturer, and Killer - Chronic Pain Must Be Stopped, as well as its Most Effective Antidote, Opiods TRP Channels Maybe because most of us are still trying to organize our thinking about CB1 and CB2 receptors, we haven't yet read the papers about Transient Receptor Potential (TRP) channels
Part ll: PK and PD Curves Really Matter with Cannabinoids: CBD, CBC, CBN and THCV
Gummies, Softgels or Tinctures? Cannabinoids, the Human Liver, PK and PD Curves. By Andrea Holmes, Ph.D., Chief Growth Officer, Precision Plant Molecules Image credit: Edited from Shutterstock by Andrea Holmes Blood and Guts Metabolism is a broad term encompassing a wide range of biochemical processes in your body. Your metabolism
Why Do PK and PD Curves Matter with CBD, CBC, CBN and THCV?
Are you serious? Only 6-10% of the cannabinoids in my Gummy Bear engages my endocannabinoid system? By Andrea Holmes, Ph.D., Chief Growth Officer, Precision Plant Moleculs This article was originally published in the July-Aug 2020 issue of Extraction Magazine. Image credit: Modified from Shutterstock by Andrea Holmes Pharmacokinetic (PK) Curves
CBC is an Ambidextrous Phytocannabinoid. Might it be the Next “It” Cannabinoid? What do snails have to do with CBC?
Why CBC is one of the Big "4": CBC, CBD, CBG and THC In PPM's previous newsletter, we talked about Cannabichromene (CBC) being chiral, having both a right- and left-hand molecule geometry. In Nature, it is fairly rare that she produces both stereoisomers in equal proportions. The chemical term
Cannabinoids like CBC can be a “Righty” or a “Lefty” – But Let’s Keep Politics Out!
Don't worry, Naturally Occurring Molecules can be Chiral but such Phytocannabinoids are Not Making a Political Statement. Let's use Cannabichromene (CBC) as an example. First the Facts: 1. CBC is a naturally-occurring so-called "minor" cannabinoid and is increasingly in demand by formulators to make more effective remedies and medicines and may be
The Poison is in the Dose: Cannabinoids (CBD, CBN, CBC, CBxyz!) vs Tylenol Toxicity – Part II
Let's consider what you have in your home and its toxicity as we judge cannabinoids. Please recall two important definitions in the study of toxicology: LD50 is defined as the "median lethal dose" of a substance that will kill 50% of those given that amount. NOAEL is defined as
The Poison is in the Dose: Safety Profiling CBD, CBN and the Minors – Part I
Sola Dosis Facit Venenum. "The dose makes the poison." Paracelsus, a Swiss physician and chemist, is credited for this maxim. He coined it 500 years ago. His famous dictum in its full glory is: "What is there that is not a poison? All things are poison and nothing is
CBN, Carboxylesterase 1, P450, In Vitro – Huh?
Warning: Short, Technical, and No Worries if this Newsletter is not for you but only for the True Cannabinoid Geeks Dosing matters is obvious. Timing and mode of drug or supplement administration highly relevant. Even when and what you eat or drink makes a difference and can be problematic,
Is THC-Free a Unicorn in the Land of Hemp and CBD?
Do THC-Free True Whole Hemp Plant Extracts, Oils and Distillates Really Exist? Why is the Concept of THC-Free So Darn Confusing? Read on if you want to learn how to translate product labels, decipher claims, and unravel marketing lingo that hopelessly confuses matters. We can’t promise
Beyond CBD: Emerging Cannabinoids are the Future for CPG Success
The buzz around the hemp-derived plant compound cannabidiol (CBD) and its therapeutic applications has captured more attention and interest than most other novel wellness products. A stampede is underway as mainstream retailers embrace hemp-derived CBD products. And cannabinoid science continues to advance at space velocity, further influencing and driving
Precision Plant Molecules Introduces the First Commercially Available High Purity Cannabichromene (CBC) Distillate to the Global Canna Marketplace GalleryPrecision Plant Molecules Introduces the First Commercially Available High Purity Cannabichromene (CBC) Distillate to the Global Canna Marketplace
Precision Plant Molecules Introduces the First Commercially Available High Purity Cannabichromene (CBC) Distillate to the Global Canna Marketplace
CBC Distillate Oil (>90% purity and 0.0% THC) and cGMP-Processed is Now Available as a Bulk Ingredient or Add-in to CBD Extracts from Colorado-based PPM for Consumer Branded Products Companies Making Innovative, Effective and Distinctive Health and Wellness Products DENVER, Aug. 27, 2019 /PRNewswire/ -- Cannabichromene (CBC) continues to be studied
Private Nebraska university to offer cannabis courses
CRETE, Neb. (AP) — A private university in Nebraska, a state which bars recreational and medicinal marijuana, plans to offer an online program this fall that will cover the science, cultivation, processing and regulation of marijuana and hemp. Doane University in Crete will offer the three-course program, which will
Mother Nature’s Genius: Understanding Phytosynthesis Reveals Access to Naturally Occurring but Rare Minor Cannabinoids with Therapeutic Properties GalleryMother Nature’s Genius: Understanding Phytosynthesis Reveals Access to Naturally Occurring but Rare Minor Cannabinoids with Therapeutic Properties
Mother Nature’s Genius: Understanding Phytosynthesis Reveals Access to Naturally Occurring but Rare Minor Cannabinoids with Therapeutic Properties
Mother Nature's Genius: Understanding Phytosynthesis Reveals Access to Naturally Occurring but Rare Minor Cannabinoids with Therapeutic Properties Because botanical medicine is inconsistent by Nature, Cannamimetics™ allows a smoothing and enhancement of the variability in extracts and concentrates made from plants, harvest to harvest, to ensure consumers are afforded the
Should we give the FDA a Break?
Plant Medicine and CBD Doesn’t Quite Fit Their Standard Operating Procedure The randomized, double-blind controlled studies that became standard in the 1950s for drug clinical trials are not well suited for multi-compound natural products because having more than one bioactive phytocompound exponentially increases the variables that need to be
Hemp Family Tree and Cannamimetics
Hemp Family Tree and Cannamimetics Cannamimetics simply means following Mother Nature’s lead. It is well known and extensively researched that during a hemp plant’s growth, various enzymatic, oxidation, photochemical and other bioprocesses produce cannabinoids and other bioactive compounds, transforming them during the course of the plant’s growth cycle. At
Greetings from Precision Plant Molecules (PPM)
Greetings from Precision Plant Molecules (PPM) We are introducing PPM, a science-based, non-psychotropic cannabinoids processor and supplier, serving the most exacting consumer products companies worldwide as a trusted supply chain partner. PPM’s proprietary hemp extraction, refinement, purification technologies, and its state-of-the-art analytical testing and R&D lab instrumentation ensure its
Finally! Democrats and Republicans Agree on Something . . . CBD
Top 10 Reasons Why The Red and Blue are Pro-CBD (and CBG, CBN, CBC) #10 The opioid crisis needs new pathways to decrease its tragic human consequences. CBD appears to be one such approach. #9 Pain hurts. Less pain is better. No one wants to be chronically inflamed. Is
Garbage In, Garbage CBD Out
Dirty CBD: Dirty, Dangerous and Dozens of Them Pesticides, Heavy Metals, Residual Solvents, Mycotoxins, Yeasts, Molds, E.Coli and Salmonella Great care and expertise (and of course accurate testing) from the field to the final CBD formulation must be taken by farmer and processor alike to ensure a safe and
The Three Basics of a Trusted, Reliable, Consistent and Superior Quality Supply Chain Partner
The Three Basics of a Trusted, Reliable, Consistent and Superior Quality Supply Chain Partner Is your CBD processor compliant with regulatory bodies? Do they document and verify all product and source materials? Do they prioritize their consumers, and thus, value safety above all else? Here are three basics that
Precision Plant Molecules Frustrated with your Third-Party Test Results?
Precision Plant Molecules Frustrated with your Third-Party Test Results? Have you ever wondered why different third-party testing labs can test the same samples or batches, but then provide varying test results? Have your potency results ever been reported as > 100% CBD? LET’S SHED SOME LIGHT ON THESE MYSTERIES.
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